Aging individuals become very enthusiastic when they discover something that produces animmediate result.
Life Extension® members often send us samples of dietary supplements they claim haveenhanced their sexual performance. These members are elated that a purported “natural” product produces such striking erection-inducing benefits and want us to inform other members.
When we try these products, we find most of them do indeed work! After we assay these products, we disappointingly find out why they are so effective.
It turns out that unscrupulous supplement makers are spiking herbal preparations with prescription drug ingredients found in Viagra®, Levitra®, or Cialis®.
So when we started getting calls about another “natural” male sex product, we were skeptical. We were impressed that fivedifferent clinical studies documented the efficacy of the nutrient combination, but we wondered, is this just another drug-spiked product pretending to be a dietary supplement?
As expected, we observed the same remarkable benefits reported in the clinical studies. What amazed us, however, was that our assays did not detect any prescription drug residue in this supplement.
Based on its underlying mechanisms of action—backed by solid scientific data—it would appear that this nutrient combination not only produces a rapid improvement in male sexual function, but may also confer significant benefit to thevascular system as well.
Erectile dysfunction is often associated with coronary artery disease.1
A nutrient formula that improves male erectile capability may very well protect against heart attack and stroke as well. This article describes the science behind this drug-free male sex enhancer.
Erectile Dysfunction Associated with Vascular Disease
Mainstream doctors generally resort to one of three FDA-approved prescription drugs (Viagra®, Cialis®, or Levitra®) to treat patients suffering from mild erectile dysfunction (ED)—with mixed results. As Mayo Clinic professor of urology Dr. Ajay Nehra recently told the New York Times, “the medications do not work for about half of the men with ED.”2
Although these drugs may help some men with ED to achieve temporary erections sufficient for sexual activity, they donothing to treat chronic endothelial dysfunction, one of ED’s stealth causes.
The unfortunate reality is that many aging men remain unaware of the link between ED and vascular disease. They go to their doctors seeking help for sexual dysfunction, get a prescription, and leave with no idea of the creeping health dangers that may lie in store for them.
These dangers are real. “Erectile problems may show up about three years before a cardiovascular event such as a heart attack or stroke,” Dr. Ira Sharlip reported in the same New York Times article.2
Prescription drugs for ED can cost as much as $15 per pill.2 They are often accompanied by an array of side effects ranging from indigestion,3 flushing,4 blurred vision,5-7 hearing loss,8,9 congestion,10 and headache11 to more serious health problems, from neurologic disorders12 to heart attacks.3,13
These drugs provide short-term relief to ED sufferers by relaxing the smooth muscles that line the arteries, thus increasing blood flow into arteries that supply the penis. In those instances when ED is the result of plaque buildup in penile arteries, these drugs offer no long-term benefit.
For men interested in achieving optimal health—including dynamic sexual health—a better option is now available.
A Unique Strategy to Support Endothelial Health—and Restore Potency
Researchers have developed a unique natural strategy for management of erectile dysfunction that includes a blend ofPycnogenol® (French maritime pine bark extract) and L-arginine aspartate, an amino acid chelate; combined with icariin, a flavonoid compound used in Chinese herbal medicine.
The interaction of these three ingredients creates a unique strategy that promises to tackle erectile dysfunction from multiple angles.
The nutrients’ underlying mechanisms of action are innovative yet elegantly simple. Here’s how it works: to get an erection, you need adequate blood flow. This requires the relaxation of the smooth muscle in the arteries of the penis. The chemical compound nitric oxide triggers this process of relaxation, increasing the blood flow to the penis required for an erection.
Endothelial cells are responsible for nitric oxide production. They release nitric oxide synthase, an enzyme that catalyzes the production of nitric oxide from L-arginine. This process is essential to maintaining an erection. Dysfunctional endothelial cells, disabled by plaque buildup, can no longer produce enough of this enzyme.30
Pycnogenol® stimulates endothelial nitric oxide synthase to produce nitric oxide in the artery linings from the amino acid L-arginine, yielding sufficient bioactive nitric oxide to maintain an erection.31 At the same time, icariin acts to block the enzyme responsible for causing erections to subside, known as phosphodiesterase-5 (PDE5).32
Interestingly, these nutrients not only promote erections, but also enhance male fertility and endo-thelial health. In other words, numerous distinct modes of action work together to produce a broad array of clinically proven health benefits. Meanwhile, prescription erectile dysfunction drugs such as
Viagra® support penile erection primarily by blocking the action of PDE5, without delivering any other benefit.
Pycnogenol® and L-arginine Aspartate: A Clinically Proven, Long-Term Alternative to ED Drugs
The efficacy of Pycnogenol® and L-arginine aspartate has been tested in five independent clinical studies. All of these studies showed that male sexual function was restored during supplementation with these ingredients.33-37 Patients also reported an increase in sexual dreams and fantasies and more frequent morning erections. Their partners noted higher sexual interest and enhanced sexual performance.38
The first clinical trial to report successful treatment of erectile dysfunction with Pycnogenol® and L-arginine aspartate involved 40 men between 25 and 45 years of age suffering from mild ED. After treatment with arginyl aspartate (which provided the equivalent of 1.7 g L-arginine per day) for one month, only 2 patients (5% of all patients) experienced normal erections. During a second month of treatment, 80 mg Pycnogenol® per day was added to the arginine regimen and yielded a significant improvement, with 32 patients (80%) enjoying normal erections. A third month’s treatment with L-arginine, together with an increased amount of Pycnogenol® (120 mg per day), further increased the number of patients with restored normal erectile function. At the end of the trial, 37 patients, equivalent to 92.5% of all participants, achieved normal erectile function.35
Source : Life Extension